Apnea

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Lack of sleep can lead you to eat larger portions of high-calorie foods and increase your long-term risk of weight gain, according to a small new study. Swedish researchers asked 16 normal-weight males to choose their ideal portions of high-calorie meals and snacks. They did this when they had a normal night of about eight hours sleep and again when they went a night without sleep.

The participants chose larger portion sizes after the night with no sleep. They did this both before and after a breakfast, which suggests that sleep deprivation increases food intake regardless of whether a person feels full, said study author Pleunie Hogenkamp, of Uppsala University.

“Bearing in mind that insufficient sleep is a growing problem in modern society, our results may explain why poor sleep habits can affect people’s risk to gain weight in the long run,” Hogenkamp said in a university news release.

The study was published online Feb. 18 in the journal Psychoneuroendocrinology. In a previous study, the same team of researchers found that young, normal-weight men who went a single night without sleep had increased activation of a brain region involved in the desire to eat.

Although the study found an association between lack of sleep and increased appetite for high-calorie foods, it did not prove a cause-and-effect relationship.

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Sleep Apnea Prevention Project (S.A.P.P.) Video Launches Worldwide With Warren Sapp to Help Save Millions of Lives

Bioengineer, Sleep Apnea Expert and Zyppah Inc. Founder Dr. Jonathan Greenburg and Super Bowl XXXVII Champion Warren Sapp have joined together to raise global awareness about the importance of getting tested and treated for snoring and obstructive sleep apnea. The global awareness health initiative, Sleep Apnea Prevention Project (S.A.P.P.), released the first video segment of a documentary of Sapp undergoing sleep apnea testing and treatment.

In January, Sapp was tested and diagnosed with obstructive sleep apnea. Through the video, viewers will gain exclusive access to the real-life experiences of the sports legend as he embarks upon a personal journey to understand the root cause of sleep apnea and the importance of getting tested. Viewers can watch Sapp as he undergoes testing and learns about the treatment options available to cure his sleep apnea.

The purpose of the S.A.P.P. is twofold:

1. GLOBAL AWARENESS: The project delivers an impactful message to the media, medical community and the millions who think of snoring as a nuisance. It illustrates how snoring, a warning sign of a more serious medical issue, is closely linked to Sleep Apnea. It also explains how untreated sleep apnea leads to serious health risks like stroke, heart disease, high blood pressure, Alzheimer’s and cancer.

2. PATIENT EDUCATION: The project provides a clear message explaining the root cause of snoring and sleep apnea. The documentary illustrates medical advances that make it more convenient to get tested and treated. It compares the patient experience and results of the home sleep test to those conducted in sleep labs. It explains the various treatments available (surgery, CPAP and oral appliances) and how these methods work to cure sleep apnea.

It is estimated that over 100 million people worldwide have sleep apnea and 80% are undiagnosed. Delivering the message that early detection and treatment of sleep apnea can extend and save lives is the goal of S.A.P.P. For more information and links to the video, follow Warren Sapp on Twitter @WarrenSapp

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The British Snoring and Sleep Apnoea Association is launching a UK-wide survey into public awareness of the condition, with the aim of testing public knowledge about signs, symptoms and health risks associated with sleep apnoea.

To make it the most comprehensive survey yet, the association is looking for adult participants from all walks of life, saying participation will be valuable whether people have the condition or think they may have it, know somebody who has it, or even know nothing at all about it.

Marianne Davey, Msc, director of the British Snoring and Sleep Apnoea Association, said around half the UK population snores, or is directly affected by a snorer:

“Sleep apnoea is an everyday condition that no-one has ever heard of. Quite a few of us suffer it and many of us come across it in friends and family members, yet so few of us know what it is or even what it’s called. So we’re now launching a UK-wide public survey into public awareness of sleep apnoea, what it is and how to deal with it, which will help us tackle the problem. We welcome a wide range of participants, from those who know they suffer from sleep apnoea to those who’ve never even come across it.”

The survey will run until the end of January and the results will be published during National Stop Snoring Week, which will run from April 22 to 27.

The survey can be found on the front page of the association’s web site at: www.britishsnoring.co.uk

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David Volpi, otolaryngology surgeon, writes in the Huffington Post that researchers are finding that US veterans are 5 times more likely to be diagnosed with sleep apnoea than the general population.

“According to the U.S. Department of Veterans Affairs (VA), one out of every five war veterans has been diagnosed with OSA — compared with only five out of 100 civilians in the general population. And between 2008 and 2010, the number of veterans who received medical benefits related to sleep apnea grew by 61 percent, from 39,145 cases in 2008 to 63,118 cases in 2010.

“These numbers beg the question: Why do war veterans suffer from sleep apnea more than non-war veterans and civilians? Some VA doctors believe that it is due to the high number of repeat deployments to Iraq and Afghanistan — soldiers are being exposed to higher levels of dust, smoke, stress and violence.”

But what is at the core of this connection between war, OSA and other related conditions, such as daytime sleepiness, memory loss, a decrease in work productivity, obesity, heart disease, diabetes, and hypertension? Researchers at the Wayne State University (WSU) School of Medicine are beginning to find out.

The research shows that:

“Those who left Iraq after the war began and suffered from mental disorders such as post-traumatic stress disorder (PTSD) and depression and self-rated their physical health as worse than their actual health were 43 times more likely than pre-Gulf War immigrants to report OSA and later develop major chronic health issues, such as cardiovascular disease.”

This research was published in Psychosomatic Medicine in October 2012.

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It is possible that pregnant women can develop sleep apnoea during pregnancy. In studies of non-pregnant populations, a 20 % weight gain has a very significant impact on the development of OSA. Since pregnant women often have similar weight gains it is theoretically possible that many will develop breathing problems that can affect the developing fetus.

Snoring is the lowest level of sleep disordered breathing. Only 4% of healthy young women snore; the fact that reports of snoring increase to 25% of pregnant women by the third trimester, points to other possible negative side-effects of compromised breathing. The more overweight a woman is before she gets pregnant, the more likely there will be alterations in her breathing at night. Studies of pregnant women show that snorers have higher blood pressure than non-snorers.

Sleep apnoea is known to increase blood pressure in patients, in the beginning this is seen only during sleep and could be missed at a medical appointment. There is a pregnancy-induced hypertension that can develop after the 20th week of pregnancy and can cause many problems with the developing baby and the mother’s health. When this gets out of control, it is called preeclampsia or, worse yet, eclampsia and can be fatal. Known risk factors for preeclampsia include family history, advancing maternal age, obesity, chronic hypertension and kidney disease.

As of now, no one knows if sleep apnoea, and the intermittent lack of oxygen it causes at night, causes the blood vessel breakdown in the placenta seen with preeclampsia or if the retention of fluid from the preeclampsia causes the breathing problems due to tissue swelling all over the mother’s body. Obstetricians are always on the lookout for this condition and will treat it aggressively.

Treatment of Sleep Apnoea during pregnancy:

Who should be treated?

Any woman who is diagnosed with severe sleep apnoea or who has drops in her blood oxygen level below 90% must be treated as quickly as possible. If the mother is not breathing properly at night, the fetus can suffer growth retardation which impacts the baby’s survival after delivery.

How should she be treated?

CPAP (Continuous Positive Air Pressure): There is no other option that will be as helpful for the fetus. It is not sexy, or comfortable, but it is only required during the remainder of the pregnancy and will help protect the baby. Oral appliances, though effective, require time to fabricate and up to three months to be maximally effective. By the time effective oral appliance therapy is instituted, the pregnancy will be over.

Surgery: is less effective than any other therapy for sleep apnea and not an approach to be taken during pregnancy.

What to do after delivery?

Women who develop sleep apnoea during pregnancy should have a follow-up sleep study after regaining her normal weight (2-3 months after delivery) This will verify if the sleep apnea has resolved. Some women take longer to shed the extra weight of pregnancy and may continue to have sleep apnea. Since sleep apnea makes people feel sleepy, and a new baby also disrupts a mother’s sleep, treatment is necessary to keep the new mother from experiencing severe sleep deprivation. Some researchers have wondered if this loss of sleep may be part of the cause of “post-partum depression”.

Source: Pien GW; Schwab RJ. Sleep disorders during pregnancy. SLEEP 2004;27(7):1405-17.

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German researchers have linked sleep apnoea to an increased risk of symptomless but dangerous “silent strokes”. There hasn’t been much research exploring the relationship between sleep apnoea and silent strokes, says researcher Jessica Kepplinger, MD, of Dresden University Stroke Center at the University of Technology in Dresden, Germany.

So, Kepplinger and colleagues studied 56 men and women, aged 44 to 75 years, who’d had a stroke or mini-stroke known as a transient ischemic attack. All were given a screening tool that picks up changes in breathing during sleep. Ninety-one percent periodically stopped breathing while they slept.

Then the men and women underwent brain imaging scans. Just over half had little areas of tissue death in the brain that had occurred in the past without a history of corresponding stroke symptoms – evidence of silent stroke. The more times a person stopped breathing during the night, the greater the likelihood of silent stroke, Kepplinger says.

There was no comparison group, so researchers don’t know how many people of the same ages and health status who don’t have sleep apnoea have had silent strokes.

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The New Zealand Herald has reported that a quarter of New Zealanders have a chronic sleep problem, according to the World Association of Sleep Medicine. Just over half of Kiwis (55 per cent) say they never wake up feeling refreshed, while 25 per cent report having a chronic sleep problem.

Studies by the World Association of Sleep Medicine show sleep disorders cost New Zealand at least 40 million dollars a year in lost productivity, and increases the risk of accidents and other illnesses like diabetes, cardiovascular disease and respiratory failure.

Sleep specialist Dr Alex Bartle, from the Sleep Well Clinic in Christchurch, said 10-15 per cent of the population suffer from chronic insomnia, while sleep apnoea affects up to 9 per cent of men and 4 per cent of females.

“People who keep waking up through the night and feel awful during the day, often think they’ve got insomnia, when in fact they have sleep apnoea and they keep waking up. Often, but not always, they are a different group. The insomniacs tend to be, in old-fashioned terms, buzzy people.”

Sleep disorders are treatable though, Dr Bartle said.

“A lot of people think that snoring and tolerating poor sleep is normal, but it’s not. If you’re tired all the time, even if you think that you’re getting enough sleep, there’s likely to be a problem.”

Dr Bartle said there tends to be three factors to insomnia – predisposing factors, such as genetics, what sort of job people have, what sort of stresses they face; precipitating factors, as in an event that has triggered the insomnia, such as a stressful event; perpetuating factors, which is when people have short-term sleeping problems but have not corrected it.

Dr Bartle said people who are using sleeping pills long-term should seek professional assistance with their sleeping.

“In the short term they can be great, but medium-long term they are not helpful,” he said. “People are happy taking a pill because it does help them sleep. The problem is they become less effective, and people take more.”

 

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A new British study suggests that moderate-to-severe sleep apnoea can reshape the heart, increasing its size, thickening its walls and reducing its ability to pump blood throughout the body.

However, the study also found that at least six months of continuous positive airway pressure (CPAP) treatment can help restore the heart’s size and function to nearly normal levels. CPAP uses a mask to deliver pressurised air into the airway of sleepers.

“To the best of our knowledge, this is the first study to provide a comprehensive assessment of left ventricular [heart] structural and functional parameters using advanced echocardiograms in otherwise healthy apnea patients,” said Dr. Gregory Lip, a researcher at the University of Birmingham Center for Cardiovascular Sciences, in England, in a journal news release.

According to Lip, the study shows that sleep apnoea “could be crucial” to the development of a certain type of heart dysfunction “that can lead to heart failure and increased mortality if left untreated.”

The researchers used two- and three-dimensional echocardiograms and Doppler imaging of heart muscle tissue to examine 40 people with moderate-to-severe obstructive sleep apnea, 40 people with high blood pressure and 40 people with no health concerns.

The study, published in Circulation: Heart Failure, revealed the patients with obstructive sleep apnea had abnormally shaped hearts. The hearts of those with sleep apnoea also functioned at the same level as those of patients with chronic high blood pressure.

Patients with sleep apnoea “may have cardiac abnormalities that often are undetected, but will improve with CPAP,” Lip reasoned. “Patients also need to understand that obstructive sleep apnea is not a benign disorder, but that their risk of heart problems can be easily treated with CPAP.”

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According to a new report by iData Research, the leading global authority in medical device market research, the European anesthesia, respiratory and sleep-management device market was valued at over $1.4 billion in 2011. By 2017, this market is expected to reach almost $2 billion, fueled by the rapidly growing telehealth/homecare therapeutic sleep-apnea and ventilator segments. Philips Respironics, ResMed and CareFusion are leading these markets, despite growing competition.

“Sleep disorders are becoming much more widely diagnosed in Europe, which is driving the demand for more advanced devices that can diagnose, treat and monitor in the home,” says Dr. Kamran Zamanian, CEO of iData. “Philips, ResMed and CareFusion are leaders in this space, however many other companies have released products in a bid to gain share in this lucrative market.”

The report states that the market for automatic positive airway-pressure (APAP) devices, which automatically detect apneic events, are expected to be the fastest-growing segment. The U.K. and France are leading in sales growth, however there is expected to be a dramatic increase in demand in Germany, Spain and Austria.

Additionally, the ventilator segment is expected to see strong growth fueled by increased sub-acute and homecare usage as well as new remote-monitoring ventilators. Philips narrowly leads this market with their non-invasive homecare ventilators, but faces strong competition from ResMed.

 

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The September issue is now out:

Snore Centre Patient eNewsletter September 2011

 

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